Do MIC injections help with weight loss?

MIC injections are not a stand-alone weight loss treatment. They can support fat metabolism and energy production as part of a broader plan that includes diet, movement, sleep, and stress management. Results vary based on the whole program.

What is the difference between MIC and B12? Can I get them together?

MIC includes methionine, inositol, and choline. B12 is cobalamin and supports red blood cell production and nerve health. Many clients receive MIC with B12 in the same visit when clinically appropriate. We typically use methylcobalamin.

How often should I get MIC injections and how long until I notice a change?

Frequency is individualized. A common starting plan is weekly injections for 4 to 6 weeks, then reassess. Some people notice changes in energy or appetite regulation within a few weeks when MIC is combined with nutrition and lifestyle support.

Who should avoid MIC injections?

You should avoid MIC if you have a known allergy to any component. Use caution with significant liver disease, severe depression, bipolar disorder, or if you are pregnant or breastfeeding. We screen for contraindications during your evaluation.

What are the possible side effects?

Most people tolerate MIC well. Possible effects include brief soreness at the injection site, mild headache, nausea, or digestive changes. Serious reactions are rare but require medical attention. Tell us about any symptoms after an injection.

Do I need an appointment or labs first?

Yes. An evaluation is required to confirm that injections are appropriate and safe. Labs may be recommended based on your history and goals. Many insurance plans cover the evaluation visit when medically appropriate.

How do I book an MIC or B12 injection?

Schedule through our Nutrient Injections page on the Pacific Clinic of Natural Medicine website. Choose MIC, B12, or a combined visit and we will confirm the best option during your evaluation.

MIC Injections: Supporting Metabolism, Liver Function, and Sustainable Energy

Q: What are MIC injections?

MIC stands for methionine, inositol, and choline. These nutrients support methylation, fat metabolism, and liver function. In our clinic MIC is offered as a nutrient injection and may be paired with vitamin B12 when appropriate.

Dr. Teresa True
Oct 21
5 min read

If your metabolism feels sluggish, or you’re doing everything “right” but still not seeing results, there’s often more going on beneath the surface. At Pacific Clinic of Natural Medicine, we look beyond calories and exercise to uncover the metabolic and biochemical factors that influence how your body burns fat, detoxifies, and maintains steady energy.

For many patients, targeted MIC injections, a combination of Methionine, Inositol, and Choline, can help restore that balance naturally and safely.

What Are MIC Injections?

“MIC” stands for Methionine, Inositol, and Choline, three lipotropic (fat-metabolizing) nutrients that play key roles in how the body processes fat and supports liver health. They help your body convert fat into usable energy, prevent fat accumulation in the liver, and support healthy detoxification pathways.

At PCNM, MIC injections are often combined with methylcobalamin (active B12) for an additional energy and metabolism boost.

Why Our Approach Is Different

You may see “skinny shots” or “lipo injections” advertised in spas and walk-in vitamin bars. That’s not what we do here. Our injections are part of a comprehensive, medically supervised program that is customized using lab data and clinical insight.

We evaluate nutrient levels, liver markers, hormones, thyroid, and adrenal balance before deciding whether MIC is appropriate. This helps ensure your injections actually address what your body needs, and that they’re done safely and effectively. It also helps ensure we aren't missing something important, such as thyroid disease, nutrient deficiencies, adrenal imbalances, hormone imbalances and more. These can all be underlying reasons why weight loss isn't happening normally.

The last thing we want to see is someone who has struggled with weight loss and it was because of underlying thyroid disease that went undiagnosed because no one bothered to check a simple lab test. In these cases, turning around the hypothyroidism is really all they need.

How MIC + B12 Work Together

Methionine – an essential amino acid that supports fat metabolism and reduces liver fat buildup.
Inositol – improves cellular insulin signaling and supports mood and brain function.
Choline – helps transport and metabolize fats and cholesterol; crucial for liver detoxification.
Methylcobalamin (B12) – enhances energy production, red blood cell formation, and neurological function.

Together, they create a synergistic effect: better fat metabolism, improved energy, and healthier liver function.

Clinical Benefits of MIC Injections

Supports healthy fat metabolism and liver detoxification
Enhances natural energy without stimulants
Promotes healthy cholesterol balance
Supports adrenal and thyroid function indirectly through improved metabolism
Complements weight-management or hormone-balancing programs

Who Might Benefit

You might consider MIC injections if you experience:

Slow or stubborn metabolism
Fatigue or poor recovery from stress
Hormonal weight changes
Signs of fatty liver or poor detox capacity
Chronic stress or over-reliance on caffeine

Safety and Monitoring

Because these nutrients influence methylation and liver pathways, professional supervision is essential. All injections at Pacific Clinic of Natural Medicine use pharmaceutical-grade nutrients and are given only after reviewing your medical history and labs.

We use methylcobalamin (B12 5000 mcg/mL), not synthetic cyanocobalamin, and follow sterile, evidence-based procedures.

How MIC Injections Compare to GLP-1 Medications

GLP-1 agonists like Ozempic®, Wegovy®, and Mounjaro® have become popular for weight management — and for some patients, they can be helpful. But they’re not a long-term solution for everyone. Many people experience digestive side effects, nutrient depletion, or rebound weight gain when the medication is stopped.

Our approach at Pacific Clinic of Natural Medicine focuses on restoring healthy metabolism from the inside out, rather than overriding it with pharmaceuticals.

MIC injections can be a safer, more sustainable option when used as part of a medically guided plan.

GLP-1 Medications	MIC Injections + Nutrient Therapy
Work by slowing gastric emptying and reducing appetite	Support natural fat metabolism and liver detoxification
Often cause nausea, bloating, constipation, or muscle loss	Gentle and restorative — no digestive suppression
May lower appetite but don’t correct metabolic imbalance	Address underlying nutrient and mitochondrial deficiencies
Require ongoing use to maintain results	Can be used short- or long-term with personalized lab monitoring
Expensive, often not covered by insurance	Affordable, direct payment pricing, no insurance headaches.

In short: GLP-1 drugs can turn the metabolism off. MIC injections help turn it back on, safely, gradually, and with nutrient support.

We often help patients transition away from GLP-1s by restoring their natural metabolic rhythm through nutrient optimization, hormone balancing, and digestive repair.

Getting Started

MIC injections are available to established patients or during a Preventative Wellness Exam. This type of preventative visit is often covered 100% by insurance. Your visit includes a full health review and baseline labs to ensure these nutrients are appropriate and to personalize dosing for long-term metabolic support.

Learn more at pacificnatmed.com/nutrient-injections

FAQs:

1. What does MIC stand for?

MIC stands for Methionine, Inositol, and Choline — three key nutrients that support fat metabolism, liver health, and energy production.

2. Are MIC injections safe?

Yes, when given under medical supervision with proper screening. We use sterile, pharmaceutical-grade nutrients and evaluate your labs to ensure safety.

3. How often should I get MIC injections?

Most patients start with once or twice weekly injections for 4–6 weeks, then adjust to every 2–4 weeks for maintenance. Your exact schedule depends on your goals and lab results.

4. Can MIC injections help with weight loss?

They support healthy fat metabolism and liver detoxification, which can make weight management easier, but nothing is a magic bullet. We combine them with lifestyle, hormone, and metabolic assessments for real results.

5. What’s the difference between your MIC injections and spa “skinny shots”?

Ours are physician-formulated and lab-guided using methylcobalamin (B12) and verified nutrient concentrations. Spa shots often use low-grade compounds and skip medical evaluation — risking imbalance or ineffective results, or even missing important diagnosis of underlying medical conditions.

6. Do I need labs before getting MIC injections?

Yes. We check nutrient levels, liver function, and metabolism markers to make sure MIC is appropriate and safe. It’s part of what makes our approach more effective than generic shot bars.

7. Can I combine MIC injections with B12 or vitamin D?

Yes, MIC is often paired with B12 for synergistic energy and metabolism benefits. Vitamin D injections can also complement the protocol, though they’re administered separately.

References

National Institutes of Health. Choline – Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/
National Institutes of Health. Inositol – Fact Sheet for Health Professionals. https://ods.od.nih.gov/factsheets/Inositol-HealthProfessional/
Lu SC. Regulation of hepatic glutathione synthesis: current concepts and controversies. FASEB J. 1999;13(10):1169–1183.
O’Leary F, Samman S. Vitamin B12 in health and disease. Nutrients. 2010;2(3):299–316.
Healthline. Lipotropic Injections: Do They Work for Weight Loss? https://www.healthline.com/health/lipotropic-injections

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